Ketamine Treatment Methods

Compare IV infusions, IM injections, nasal spray, sublingual tablets, and other ketamine delivery methods.

Quick Comparison

Compare delivery methods at a glance. Click any row for the full guide.

Method	Setting	Bioavailability	Cost / Session	Session Length
IV Infusion	Clinic	~100%	$400-800	40-60 min
IM Injection	Clinic	~93%	$350-600	30-45 min
Spravato	Certified clinic	~48%	$600-900*	2+ hours
Sublingual	Home	25-35%	$150-350	1-2 hours
Troches	Home	25-30%	$100-300	1-2 hours
Nasal Spray	Home	~45%	$200-400	1-2 hours
Compounded	Varies	Varies	$100-400	Varies
At-Home Therapy	Home	25-45%	$200-500/mo	1-2 hours

* Spravato may be partially covered by insurance. Costs vary by clinic and region.

Detailed guides covering procedure, costs, effectiveness, and patient experiences.

Complete guide to IV ketamine infusions. Learn about the procedure, typical costs, session duration, and what to expect during treatment.

Learn about intramuscular ketamine injections as an alternative to IV infusions. Compare effectiveness, cost, and convenience.

Guide to sublingual ketamine treatment. Understand dosing, effectiveness compared to IV, and how at-home protocols work.

Everything about Spravato (esketamine), the FDA-approved nasal spray for treatment-resistant depression. Coverage, REMS program, and comparisons.

Learn about ketamine troches (compounded lozenges) for at-home therapy. Dosing, how to use them, and how they compare to other forms.

Compare compounded ketamine nasal spray with Spravato. Understand differences in cost, availability, dosing, and insurance coverage.

Understand compounded ketamine medications. Learn about compounding pharmacies, safety considerations, and different formulations available.

Guide to at-home ketamine therapy programs. Compare telehealth providers, understand safety protocols, and learn about costs and requirements.

Search our directory to find clinics that offer the treatment methods you are interested in.